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For the scenario of "Current obesity treatment with proven efficacy," research data suggests Semaglutide may be more relevant

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These studies consistently report favourable renal outcomes (e.g., eGFR, macroalbuminuria, or serum creatinine levels) with GLP-1 receptor agonists

The drugs known as s known as GLP-1 agonists work by triggering insulin release, blocking sugar production in your liver, and making you feel full for longer by slowing the flow of food through the digestive system