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Treatment with a B cell-depleting CD20 antibody attenuates disease, whereas transfer of IgG from DIO mice rapidly induces insulin resistance and glucose intolerance
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It is known to help improve triglyceride levels, which can counter high levels of bad cholesterol
In summary, the patient-derived hepatocyte organoids and periportal assembloid models we present here hold the potential to initiate a new era in diverse areas of liver research, including in diagnostics, toxicology, personalized drug efficacy screening and cellular transplantation therapy
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