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[73] As noted above, the completely synthetic laboratory synthesis of B 12 was achieved by Robert Burns Woodward and Albert Eschenmoser in 1972, though this process has no commercial potential, requiring more than 70 steps and having a yield well below 0.01%

Vitamin B12 is stored in the liver

The NHS adult daily requirement is 1.5 micrograms a day, which a normal mixed diet covers easily and stores in the liver for years

Practical statistics for medical research

Dietary shortfall is increasingly common as more clients adopt plant-based eating, because vitamin b12 foods are almost entirely animal-derived: meat, fish, eggs and dairy, with fortified cereals and yeast extracts the main vegan options

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