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Vitamin B12 (Cobalamin) StatPearls

The body tightly regulates B12 absorption through intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its uptake in the terminal ileum

A single injection helps, but for a depleted person the effect may not last long

Ongoing Research 5-Amino-1MQ continues to be investigated across metabolism, cellular biology, and enzyme pharmacology due to its highly selective inhibition of NNMT