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doi: 10.2460/javma.2003.223.1137 16

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These tight junctions are regulated by zonulin, a crucial protein that serves as a messenger, signaling when it's time to open or close the junctions

The finding that GCLc- or GSS-deficient mice are non-viable in the embryonic period [35,36], while GCLm-deficient mice are viable and fertile with decreased GSH levels in the tissues compared to those of wild-type mice [37], suggest that GSH is essential for embryogenesis

Proceedings of the New Zealand Society of Animal Production, 62, 307-310

Current studies confirm that the two processes are linked via shared pathways such as ferritinophagy, mitophagy, and Nrf2, yet many questions remain