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After first use, pens can be stored at room temperature (up to 86F/30C) or refrigerated, and should be discarded after 56 days

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The 56-week COR-I trial studied the use of Contrave in patients with a BMI of 27 or higher and found that participants taking a combination of naltrexone and bupropion lost an average of 4.8% more weight than those given a placebo

Clean the site and allow it to dry completely before injecting