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In clinical trials for non-GI wounds, including diabetic ulcers and Mohs surgical wounds, GHK-Cu demonstrated significantly improved re-epithelialization

There is ongoing discussion about the potential negative consequences of prolonged activation of lysosomal pathways

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113,114 A review of evidence for sleep restriction as a stand-alone treatment for insomnia found it improved sleep efficiency and total sleep time, and researchers concluded it was an effective means of treating chronic insomnia