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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Kil D.Y., Vester Boler B.M., Apanavicius C.J., Schook L.B., Swanson K.S

This becomes more relevant with extended use, typically after several months

Results vary based on injury type, severity, and individual response

Nestin-CreERT2/Ai27D and Nestin-CreERT2/Ai27D/HIF1a WT/flox (Nestin-CreERT2 mice from (Imayoshi et al.) 67

Cells express hundreds, perhaps thousands of proteins that require bound metal cofactors for activity and stability (Waldron et al., 2009)

Moreover, increased expression of FAk and paxillin was observed, and it was speculated that these proteins might be involved in mediating the recovery of injured tendons [8]