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Light-activated transcription of immediate-early genes such as c-fos and JunB (165,166) causes activation of PER1 gene transcription as well as modification of the acetylation pattern of histone tails

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A consequence of this chain reaction is the eventual deterioration of membrane integrity and, ultimately, destabilization of organelles or cell membranes

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doi: 10.1111/j.1365-2133.2009.09351.x 191 PellegriniCMaturoMGMartorelliCSuppaMAntoniniAKostakiDet al

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