doi: 10.1016/j.phrs.2020.105157 103 MaoGXinDWang Q and LaiD
Overexpression of glutathione peroxidase increases the resistance of neuronal cells to A beta-mediated neurotoxicity
Y.KhanA
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Acknowledgements This research was supported by National Natural Science Foundation of China (NSFC) projects (Grant number: 201874024), and the intramural research program of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH)
According to the requirements of the national food and drug administration 'drug registration management method', the test scheme is designed and the test work is completed, and the results are as follows: (1) in the high-stability injection reduced glutathione vascular irritation test, the rabbit ear marginal vein control group, the market-sold group and the tested group have no hyperemia, hemorrhage and degenerative necrosis phenomena, and have no pathological damage, which indicates that the high-stability injection reduced glutathione (the sample with the batch number of YJ110401 is selected by the invention) does not generate irritation reaction on the rabbit ear vascular by intravenous administration