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Bruising rarely occurs but can last 1 to 2 weeks

This information is for research reference only not medical advice

Spotting when wiping during perimenopause is common, affecting around 4050% of women who track their cycles during this transition Hormonal fluctuations, particularly estrogen and progesterone shifts, cause most perimenopausal spotting Conditions like uterine fibroids, polyps, and vaginal atrophy can also trigger spotting Tracking symptoms helps identify patterns and provides valuable information for healthcare providers Heavy bleeding, severe pain, or spotting after menopause requires prompt medical evaluation Finding blood when wiping can feel alarming, especially when periods become unpredictable

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Therefore, we believe that the discovery of low-cost oral GLP-1RA analogues or synergists and the continuous elucidation of the possible mechanism of action of GLP-1 are of great significance for the expansion of the field of disease treatment

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