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Fung LK, Flores RE, Gu M, Sun KL, James D, Schuck RK, et al

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However, some women experience disrupted sleep during dose escalation phases, particularly if nausea or digestive discomfort interferes with nighttime rest

Another trial evaluated the effects of CoQ10 supplementation (150 mg daily) for 7 days preceding scheduled coronary artery bypass grafting (CABG) procedures in 40 subjects who were divided to receive CoQ10 or act as a control group

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Common adverse effects include nausea, vomiting, diarrhoea, constipation, and abdominal pain, which are usually mild to moderate and diminish over time as the dose is gradually increased