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a) EGCit linker [6] and b) Exo-EEVCit linker structure [7] Beyond these examples, other protease-sensitive sequences (e.g., GGFG, VA, AA, AAN) and linkers responsive to different hydrolases (-glucuronidase, -galactosidase, phosphatase) are expanding the toolkit (Figure 8)

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This delay in digestion can disrupt the natural rhythm of the gut, leading to side effects such as nausea, bloating, and diarrhea

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Furthermore, it has been demonstrated that neutrophils are significant in the PC microenvironment