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However, after consideration of public comments, discussed in an earlier section of this final rule with comment period, we are finalizing, effective January 1, 2026, our proposal to supplant the existing affirmation requirement with the proposed attestation statement at new ( 180.50(3)(iii), with a modification to add to the following phrase to the beginning of the attestation: To the best of its knowledge and belief,

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(van der Veen et al., 2017)

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Following ischemia-reperfusion, melatonin has been shown to reduce neuronal cell death in the ischemic brain through its potent free radical scavenging and antioxidant effects (Lee et al., 2005