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Sleep apnoea, a condition in which breathing repeatedly stops and starts during sleep, is significantly more common in men than in women, and is associated with fatigue, poor cognitive function, elevated cardiovascular risk, and reduced testosterone

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Even 20-30 minutes of walking daily helps

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They included 12 SGLT2i trials with 73,238 participants, of whom 3,065 were on a GLP-1 RA: they found that the benefits of SGLT2i on MACE were consistent regardless of background GLP-1 RA use (HR = 0.81 in patients receiving GLP-1 RA vs HR = 0.90 in those not receiving GLP-1RA) with no significant heterogeneity (p = 0.31)