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Nutrients 10 (12), 1971

-MSH binds to different melanocortin receptors to produce different effects, including the following: Increases melanin production by binding to the melanocortin 1 receptor (MC1R), stimulating the production of different enzymes, including tyrosinase

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Other Antidiabetic Medications: Metformin : Generally, no significant interactions, and they are often used together effectively

Basic residues (such as arginine) are paired with nonpolar amino acids (such as proline, alanine, valine and leucine), which have a strong inhibitory effect on tyrosinase (Zu et al., 2023)