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Pharmacokinetics, tissue distribution and metabolism of senkyunolide I, a major bioactive component in Ligusticum chuanxiong Hort (Umbelliferae)

95% CI, 1.28-3

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This is the proposed mechanism by which oxidative stress initiates and amplifies autoimmune thyroid disease: oxidized thyroid proteins immune recognition TPO antibodies (TPOAb) and thyroglobulin antibodies (TgAb) progressive thyroid destruction