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doi: 10.4088/JCP.15m10185 126

After the phagophore has reached its final size, VMP1 promotes the dissociation of contacts between the ER and the phagophore via local changes in Ca 2+ concentrations until the final scission event is then mediated by the endosomal sorting complexes required for transport (ESCRT) machinery (8083) ( Figure 1 , panel 3)