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Under normal physiology, the largest GH pulse of the day occurs during the first episode of slow-wave sleep (SWS), typically within 90 minutes of sleep onset

Some individuals carry genetic patterns that make them naturally more sensitive to GLP-1 effects, meaning they may experience stronger side effects at standard doses

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Cell Mol Biol Lett 28:76 Deragon MA, McCaig WD, Patel PS et al (2020) Mitochondrial ROS prime the hyperglycemic shift from apoptosis to necroptosis

It can also provide enhanced recovery and prevent muscles from increased fatigue