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This warning does not reflect confirmed human cases of thyroid cancer from GLP-1 use, but it has prompted careful monitoring in clinical trials and clinical practice

Well-designed clinical trials are needed to clarify the therapeutic potential of GLP-1RAs in ALS [44,45]

Encouraging results from phase IIa and IIb studies have paved the way for phase III clinical trials 6

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Over time, the body may respond to changes in routine

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