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CYP2B6 substrate drugs: In vitro studies suggest G

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Such a nanosystem could activate cisplatin by exhausting the intracellular GSH, which elevated the Pt-induced DNA intrastrand or interstrand crosslinks, thereby contributing to the anticancer efficiency of platinum drugs

doi: 10.1111/nure.12012 Summary Keywords amino acid metabolism, diabetic kidney disease, functional foods, gut microbiota, gut-liver-kidney axis, medicine food homology, natural bioactive compounds, uremic toxins Citation Sun L, Sun G, Nan Y, Wang H, Sun Y, Shi Y, Yang Y and Wang Q (2026) Gut microbiota-liver-kidney axis in diabetic kidney disease: mechanistic insights into amino acid metabolism and nutritional intervention strategies targeting natural bioactive compounds