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Oral supplementation (50150 g daily) may suit dietary deficiency without nerve involvement, but malabsorption cases require injections

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The symptoms do not identify a specific toxin, but they may justify a targeted review of environmental exposure, medications, alcohol, gut dysfunction, copperzinc balance, methylation and organ clearance

Shawn, the Drosophila homolog of SLC25A39/40, is a mitochondrial carrier that promotes neuronal survival

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Heinrich determined that a dose (D) of cyanocobalamin is absorbed at a rate of: Stephen Walsh, PhD, a mathematical modeler associated with the UK Vegan Society, has analyzed Heinrichs data and found this formula to be a better fit: Heinrichs data assumes that the cyanocobalamin is taken on an empty stomach