However, PKA-activity appears to be essential for optimal incretin effects on stimulating insulin vesicle exocytosis." 5 There have been studies performed in animal subjects that show evidence of the pleiotropic effects of GLP-1 on beta cells such as beta cell regeneration and proliferation
Some of the newer research suggests GLP-1s might help improve insulin sensitivity and reduce symptoms related to PCOS like cravings, irregular cycles, or weight gain around the midsection
10.7717/peerj.17891 [DOI] [PMC free article] [PubMed] [Google Scholar] Flint A., Andersen G., Hockings P., Johansson L., Morsing A., Sundby P
No changes in lean mass were observed after chronic treatment with the lower doses of any of the poly-agonists (Fig
Meals that took 2-3 hours to clear your stomach now take 4-6 hours
PubMed Watson JM, Jenkins EJ, Hamilton P, et al