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Retatrutide has been studied at weekly subcutaneous doses of 0.5 mg, 1 mg, 2 mg, 4 mg, 8 mg, and 12 mg in Phase 2 research
Storing the vial in a refrigerator also protects it from light, which can degrade the preservative and compromise the solution over time
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The program established a favorable safety profile but the Phase IIb endpoint did not differentiate sufficiently from placebo to support continued development for obesity