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Statistically significant difference was found between rats exposed to stress treated with Etomoxir and CMS rats receiving vehicle (p = 0.0441)

Similar observations have been made in other model organisms [97,98]

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In this case, BPTES targets glutamine metabolism, and metformin targets glucose metabolism, resulting in an optimal reduction of tumor development [38]

In addition to having a greater reduction in BMI and total daily insulin use, the GLP-1 group had better preservation of glomerular filtration rate and creatinine levels at 3- and 6-month follow-ups than the group that did not receive a GLP-1

Women experiencing menopause, individuals with thyroid disorders, or those with insulin resistance may see different results compared to metabolically healthy individuals