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doi: 10.1186/1471-2172-10-39 179 LiLSunWWuTLuRShiB

105 , 3228.e1 (2016)

Also developed by Eli Lilly, this dual agonist activates both GIP and GLP-1 receptors

Choose Semaglutide if: Youre new to weight-loss medications You want something well-established Appetite control is your main struggle Choose Tirzepatide if: Semaglutide didnt get you where you wanted You struggle with blood sugar swings or insulin resistance You want stronger, more consistent fat loss Consider Retatrutide if: You want the most aggressive metabolic support Youve plateaued on other options Youre focused on maximum fat loss potential Bottom Line All three medications work they just work differently

Status: Investigational/controlled