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Treated mice showed decreased susceptibility to muscle damage, improved muscle strength, reduced PARP activity, increased NAD + levels, and elevated mitochondrial function 254 , thus suggesting a potential therapeutic benefit of NR supplementation in DMD

The assays were performed with steps similar to those described in the product manual, and the number of propidium iodide-positive cells was calculated via the high-concentration imaging system Operetta CLS (PerkinElmer, USA)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Lin H.V., Wang J., Wang J., Li W., Wang X., Alston J.T

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