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In some embodiments, the otic formulation or composition comprises between about 0.001% to about 99.99% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Thioctic acid can be injected directly into a vein using a syringe and perfusor, even with a minimum injection time of 12 minutes

Unlike pills or drinks that must battle through your digestive system (where up to 80% of nutrients can be lost!), IV therapy achieves 100% absorption by bypassing digestion entirely

which can be as small as 50 nanometers, to permeate the lipid bilayer of cells

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