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If you carry variants linked to rapid rebound, your provider may recommend continuous therapy, higher maintenance doses, or dual-compound therapy (GLP-Squared) for stronger appetite suppression

You are losing the GIP receptor activation that contributed to tirzepatide's effects

Full titration schedule with units at every concentration The standard semaglutide titration schedule follows a 20-week escalation protocol designed to minimize side effects while gradually reaching the therapeutic dose

It is not known whether this was due to the semaglutide or some other factor

Most protocols recommend picking one general area for consistency, then rotating specific spots within that area