Two variables were combined at the midpoint to generate 2D and 3D graphs while maintaining the third-factor constant
This leads to the development of the cell danger response
Microplastics cause changes in protein structure [2], interact with cell membrane lipids, induce transcription of inflammatory genes and increase production of pro-inflammatory cytokines, lead to dysfunction of the endoplasmic reticulum, mitochondria and induce cell death due to oxidative stress
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