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Contraindications, Drug Interactions, and Monitoring Important precautions include: Avoiding use in active, untreated malignancies due to theoretical tumor-promotion concerns Using caution with immunosuppressants Monitoring blood pressure and liver enzymes if treatment exceeds six weeks Consulting a healthcare professional if you have bleeding disorders or take anticoagulants Bodybuilders who use multiple compounds should be especially careful because side effects and interactions may be harder to identify

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Haematological malignancies: Myeloproliferative disorders (polycythaemia vera, chronic myeloid leukaemia) and some lymphomas increase B12-binding proteins, particularly haptocorrin, raising measured serum levels

2001 Sep;131(9 Suppl):2515S-22S