2020;151 suppl 1:37-44
The DeepChem platform integrates multi-omics data (genomic, epigenetic, metabolomics) and drug interaction networks through deep learning models (such as neural networks) to accurately predict gemcitabine synergistic drug regimens ( Gemcitabine + ATR inhibitor regimen generated by DeepChem achieved an objective responRegarding the latest se rate (ORR) of 38% in platinum resistant bladder cancer, which is 2 times higher than the traditional regimen
Eryptosis and aging Multicellular organisms are subject to the biological process of aging, and recently 12 different hallmarks of aging have been defined: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, dysregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis [415]
PNAS, 115(43), 1083610844
Natural antioxidant Because it is made within your body, glutathione works exactly where it is needed
E2, whose effects are partially mediated by GPER, can promote the proliferation of diverse thyroid cancer cell lines (WRO, FRO and ARO) [205]
