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From a research perspective, scientists examine how BPC-157 behaves in solution under defined laboratory conditions

Disruptions in the intrinsic factor (IF) pathway, including impaired IF production due to autoimmune conditions (pernicious anemia), damage to the ileum from diseases like Crohns or celiac disease, or surgical resection of the ileum, can severely impair B12 absorption

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Most patients experience improved flexibility and reduced discomfort within 24 weeks , with continued improvement as tissues repair and inflammation subsides