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The FDA has stated explicitly that these salt forms are "different active ingredients" and that the agency "is not aware of any lawful basis for their use in compounding." The practical concern is that salt forms may have different chemical and pharmacological properties

CrossRef 6-shogaol suppresses MAPK14 to attenuate endoplasmic reticulum stress and alleviate alcohol-associated liver disease Fucheng Zuo, Qixiang Wu, Xinyu Lin, Shanshan Ge, Ran Wang, Tao Xu, Qi Yan Phytomedicine .2026

Jama 206:642645