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However, despite their widespread use, some aspects of GLP-1 function, especially pertaining to its role in the central nervous system (CNS), remain unexploredan important gap considering the increasing number of patients receiving this treatment (22, 23)

The organic layer was dried over anhydrous Na 2 SO 4 , filtered, concentrated in vacuo, and purified by silica gel column chromatography to give light-yellow oil pruducts 2,2-(propane-2,2-diylbis(sulfanediyl))bis(ethan-1-ol)

Theyll also check for any underlying health conditions that may need attention before starting the medication

Zhang Z, Zhai H, Geng J, Yu R, Ren H, Fan H, et al

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Similarly, a study that utilised the DOCA-salt model of hypertension observed increased plasma LPS and decreased colonic gene expression of occludin and ZO-1 [97]