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The solvent was evaporated in vacuo to give a crude mixture that was further purified by HPLC (water and acetonitrile, both supplemented with 0.1% trifluoroacetic acid) on a Cosmosil C18 AR-II column (5.0 m, 10 250 mm

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10.1111/j.1469-8137.2008.02748.x 183 VermaD

Transitioning from semaglutide to tirzepatide This direction has more clinical data supporting it because many patients have made this switch as a one-time transition