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Vitamin B12 injections are crucial for those diagnosed with conditions like Pernicious Anemia, where the body cannot absorb Vitamin B12 from food

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By inhibiting TGF- pathways and reducing collagen deposition, they protect podocytes and endothelial cells from injury, slowing CKD progression

B12 is essential for the formation of red blood cells, DNA synthesis, and the proper functioning of the nervous system

Reduced appetite and food intake on these drugs can mean reduced fluid intake, and older adults have a diminished thirst mechanism relative to younger adults

References: [1] Healthline, What is Sermorelin and How is It Used?, Armstrong, M., MD., Updated August 2025 [2] Cleveland Clinic, Circadian Rhythm, March 2024