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Computational tools such as antiSMASH [65], PREDetector [66] or PRISM [67] may be efficiently utilized to detect such BGCs, predict how they are regulated or foresee the structural core of the compound produced by those genes

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Based on potential binding regions predicted by JASPAR database, we designed specific primers targeting the binding site between c-Myc and the miR-29b-3p promoter (Table S2)