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The association between UPF and the development of ASD may arise as a consequence of dietary contaminants in UPF, such as acrylamide, leading to changes in lipid regulation and metabolism ( 4.1 Summary of key pathophysiological mechanisms UPFs may lead to several pathophysiological changes across several important cellular and biochemical pathways, which have been implicated in the development of psychiatric disorders

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This dysregulation may have downstream effects on the gut microbiome, which is known to exhibit high levels of dysbiosis in ME/CFS patients (Morten et al., 2018

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