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By retaining or excreting water and electrolytes, healthy kidneys maintain blood volume and optimal hydration of tissues (Baynes 2014

254 In an obese mouse model, Lactobacillus plantarum NCUH001046 and Lactobacillus fermentum alleviated obesity development by regulating the hepatic AMPK signaling pathway and gut flora via the microbe-fat-liver axis

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Notably, despite increasing GPx activity, DHS (25 M) treatment did not protect splenic lymphocytes from radiation-induced apoptosis

The reduction in hepatic fat in HIV-associated fatty liver disease, alongside the primary visceral-fat effect, has been characterized in randomized trials, and the mechanistic follow-up identified reductions in fibro-inflammatory mediators (VEGFA, TGF-1, CSF1) that track with improvements in liver-injury scores