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Absorption Issues : Certain conditions like pernicious anaemia, celiac disease, Crohn's disease, and growth of bacteria in the stomach or small intestine can affect the bodys ability to absorb B12

Under pro-inflammatory stimulation, the association between changes in Asp levels and inflammatory factor production has attracted attention in multiple studies

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Adsorptive-mediated transport at the BBB has also been exploited to target nanocarrier systems by using cationic lipids and cell penetrating peptides to increase binding and internalization at the brain capillary endothelium [29, 30], which has a highly negative surface charge [31]

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