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Trial dosing follows a stepwise escalation from 12 mg up to maintenance doses of 4 mg, 8 mg, or 12 mg subcutaneously once weekly

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doi: 10.1007/s40291-013-0025-8 7 WangJQTengQXLeiZNJiNCuiQFuHet al

This is why some patients benefit from dose optimization or exploring alternative GLP-1 compounds that work through different pathways in your brain and metabolism

Ipamorelin and Hexarelin instead act on the ghrelin receptor (GHS-R1a) in the pituitary and hypothalamus, triggering GH release through a separate pathway

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