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There is some evidence that L-carnitine can accelerate weight loss in obese cats

Considering the roles of the JAK/STAT signaling pathway and TGF-1 in RA pathogenesis, and given that L-carnitine has been reported to modulate these pathways in other chronic conditions such as cardiovascular, pulmonary, and renal diseases, this study was designed to investigate whether similar effects could be observed in rheumatoid arthritis

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As weak agonists tend to become partial agonists when receptor density is limited 32 , this may indicate failure of the slowly internalizing compounds to maximally exploit the residual surface receptors