All of this data has clinical relevance: Polonikov , studying 4 cases of moderate to severe COVID-19, found that while the three patients with high normal plasma glutathione levels recovered quickly, the one with low glutathione levels, high plasma ROSs and ROS / GSH ratio was suffering from the most severe disease and, at the time of publication, was still ill
Proc Natl Acad Sci USA 97: 51015106 Tu BP, Weissman JS (2002) The FAD and O(2)dependent reaction cycle of Ero1mediated oxidative protein folding in the endoplasmic reticulum
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