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Some rare sermorelin side effects can include ( 6 ): Allergic reactions, such as rash, itching, or in severe cases, difficulty breathing Sleep disturbances, including vivid dreams or insomnia Water retention, bloating, or swelling in the hands and feet Joint pain or stiffness, particularly in the knees or ankles Tingling or numbness in the extremities These effects can sometimes be related to how the body processes increased GH levels

Recent research has taken advantage of the neuroprotective properties of indole-containing compounds such as melatonin, which is reduced in AD patients (Rossotti and Rossotti 1965), by combining the indole structure with other bioactive components (e.g., 8-hydroxyquinolines and tacrine) to create compounds with multiple therapeutic benefits aimed at treating AD (Gans et al