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Shanazi et al., 2015
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Lapatinib Suppresses Ferroptosis in KA-Induced Epileptic Mice To further investigate the potential molecular mechanism by which lapatinib exerted neuroprotection, the alterations of ferroptosis-related indices including 4-HNE (a common by-product of lipid peroxidation) (Figures 3A,B, KA injection resulted in the upregulation of 4-HNE levels and this phenomenon was reversed after pretreatment with lapatinib and Fer-1 (ANOVA, F (5,24) = 5.219, p = 0.009)
Prevent Diabetes and Improve the Insulin Response Increasing the Carnitine levels helps to deal with the effects of diabetes because this amino acid has incredible antioxidant properties
At the middle stages (TRL 5 to 7), the focus shifts to demonstration and prototype development
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