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NCT03819153) was a multicenter, double-blind, randomized (stratified according to the use of sodium-glucose cotransporter 2 [SGLT2] inhibitors at baseline), placebo-controlled clinical trial led by an academic steering committee and conducted at 387 international sites, with a median follow-up of 3.4 (interquartile range 2.94.0) years

Those include Eliquis, Pfizer's blood thinner marketed with Bristol Myers Squibb, and Ibrance, a drug for advanced and metastatic breast cancer

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This effect appears related to the peptides effects on connective tissue and fluid retention

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