Sources: Heike Vogel a f g, a, f, g, c, d, e, b, HighlightsEstrogen (E) and GLP-1 interact to reduce body weight, & AbstractThe obesity epidemic continues unabated and currently available pharmacological treatments are not sufficiently effective
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After transplanting T315I-Bcr-Abl-32D/EGFP cells into C3H/HeNCrNarl mice for 7 days, the mice were treated with daily intraperitoneal injections of UK-5099 alone or in combination with JMF4073 for 14 days (Fig
Here we show morphine-induced constipation is mediated by a neural circuit from glutamatergic neurons in the paraventricular nucleus of hypothalamus (PVN Glu ) to acetylcholinergic neurons in the dorsal motor nucleus of the vagus (DMV Ach ), and subsequently to the small intestine in mice
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Some GLP-1 receptor agonists have demonstrated cardiovascular benefits in specific populations in clinical trials, but patients with thyroid conditions may have pre-existing cardiac issues that require evaluation