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Next-generation sequencingbased profiling of the reexcision sample demonstrated a deleterious somatic PRKAR1A variant associated with loss of heterozygosity encompassing the region of the second PRKAR1A allele on chromosome 17q, resulting in an ultimate diagnosis of MMNST and reversing the initial diagnosis of metastatic melanoma

Heinig R, Schaefer HG, Wensing G, Kuhlmann J

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