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Be on the lookout for serious symptoms , including redness that spreads beyond 2 inches, increasing swelling, intense pain, fever, chills, or trouble breathing

Your doctor has determined the benefits outweigh the potential risks

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And the exercise interaction backs this up: higher fitness builds a greater parasympathetic reserve (essentially, a better ability to slow your heart rate), which helps offset the sympathetic drive from GLP-1

Gender difference in cardiovascular outcomes with SGLT-2 inhibitors and GLP-1 receptor agonist in type 2 diabetes: a systematic review and meta-analysis of cardio-vascular outcome trials